Efficacy and Safety of Pembrolizumab for Heavily Pretreated Patients With Advanced, Metastatic Adenocarcinoma or Squamous Cell Carcinoma of the Esophagus: The Phase 2 KEYNOTE-180 Study

IMPORTANCE: Effective treatment options are limited for patients with advanced, metastatic esophageal cancer progressing after 2 or more lines of systemic therapy. OBJECTIVE: To evaluate the efficacy and safety of pembrolizumab for patients with advanced, metastatic esophageal squamous cell carcinom...

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Publicado en:JAMA Oncol
Autores principales: Shah, Manish A., Kojima, Takashi, Hochhauser, Daniel, Enzinger, Peter, Raimbourg, Judith, Hollebecque, Antoine, Lordick, Florian, Kim, Sung-Bae, Tajika, Masahiro, Kim, Heung Tae, Lockhart, A. Craig, Arkenau, Hendrik-Tobias, El-Hajbi, Farid, Gupta, Mukul, Pfeiffer, Per, Liu, Qi, Lunceford, Jared, Kang, S. Peter, Bhagia, Pooja, Kato, Ken
Formato: Artigo
Lenguaje:Inglês
Publicado: American Medical Association 2018
Materias:
Brief Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459121/
https://ncbi.nlm.nih.gov/pubmed/30570649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.5441
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