2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells

The present paradigm of psoriasis pathogenesis revolves around the IL-23/IL-17A axis. Dual-secreting Th17 T cells presumably are the predominant sources of the psoriasis phenotype-driving cytokines, IL-17A and IL-22. We thus conducted a meta-analysis of independently acquired RNA-seq psoriasis datas...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Le, Stephanie T., Merleev, Alexander A., Luxardi, Guillaume, Shimoda, Michiko, Adamopoulos, Iannis E., Tsoi, Lam C., Wang, Jenny Z., Alexanian, Claire, Raychaudhuri, Siba P., Hwang, Samuel T., Gudjonsson, Johann, Marusina, Alina I., Maverakis, Emanual
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458264/
https://ncbi.nlm.nih.gov/pubmed/31019502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00589
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