2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T Cells

The present paradigm of psoriasis pathogenesis revolves around the IL-23/IL-17A axis. Dual-secreting Th17 T cells presumably are the predominant sources of the psoriasis phenotype-driving cytokines, IL-17A and IL-22. We thus conducted a meta-analysis of independently acquired RNA-seq psoriasis datas...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Le, Stephanie T., Merleev, Alexander A., Luxardi, Guillaume, Shimoda, Michiko, Adamopoulos, Iannis E., Tsoi, Lam C., Wang, Jenny Z., Alexanian, Claire, Raychaudhuri, Siba P., Hwang, Samuel T., Gudjonsson, Johann, Marusina, Alina I., Maverakis, Emanual
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458264/
https://ncbi.nlm.nih.gov/pubmed/31019502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00589
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