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Extracellular Vesicles from Apoptotic Cells Promote TGFβ Production in Macrophages and Suppress Experimental Colitis

The clearance of apoptotic cells is an essential process to maintain homeostasis of immune system, which is regulated by immunoregulatory cytokines such as TGFβ. We show here that Extracellular Vesicles (EVs) were highly released from apoptotic cells, and contributed to macrophage production of TGFβ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Hua, Kasagi, Shimpei, Chia, Cheryl, Zhang, Dunfang, Tu, Eric, Wu, Ruiqing, Zanvit, Peter, Goldberg, Nathan, Jin, Wenwen, Chen, WanJun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458171/
https://ncbi.nlm.nih.gov/pubmed/30971739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42063-7
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