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Extracellular Vesicles from Apoptotic Cells Promote TGFβ Production in Macrophages and Suppress Experimental Colitis

The clearance of apoptotic cells is an essential process to maintain homeostasis of immune system, which is regulated by immunoregulatory cytokines such as TGFβ. We show here that Extracellular Vesicles (EVs) were highly released from apoptotic cells, and contributed to macrophage production of TGFβ...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Chen, Hua, Kasagi, Shimpei, Chia, Cheryl, Zhang, Dunfang, Tu, Eric, Wu, Ruiqing, Zanvit, Peter, Goldberg, Nathan, Jin, Wenwen, Chen, WanJun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458171/
https://ncbi.nlm.nih.gov/pubmed/30971739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42063-7
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