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Cytosolic processing governs TAP-independent presentation of a critical melanoma antigen

Cancer immunotherapy has been flourishing in recent years with remarkable clinical success. But as more patients are treated, a shadow is emerging that has haunted other cancer therapies: tumors develop resistance. Resistance is often caused by defects in the MHC class I (MHC I) antigen presentation...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Vigneron, Nathalie, Ferrari, Violette, Van den Eynde, Benoît J., Cresswell, Peter, Leonhardt, Ralf M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457910/
https://ncbi.nlm.nih.gov/pubmed/30135181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701479
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