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Deletion of BCG Hip1 protease enhances dendritic cell and CD4 T cell responses

Dendritic cells (DCs) play a key role in the generation of CD4 T cell responses to pathogens. Mycobacterium tuberculosis (Mtb) harbors immune evasion mechanisms that impair DC responses and prevent optimal CD4 T cell immunity. The vaccine strain Mycobacterium bovis Bacille Calmette-Guérin (BCG) shar...

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Bibliografske podrobnosti
izdano v:J Leukoc Biol
Main Authors: Bizzell, Erica, Sia, Kevin, Quezada, Melanie, Enriquez, Ana, Georgieva, Maria, Rengarajan, Jyothi
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457460/
https://ncbi.nlm.nih.gov/pubmed/29345365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4A0917-363RR
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