Glutathione Peroxidase 1 Promotes NSCLC Resistance to Cisplatin via ROS-Induced Activation of PI3K/AKT Pathway

PURPOSE: Reactive oxygen species (ROS)-induced cytotoxicity is an important mechanism by which cisplatin kills tumor cells. Glutathione peroxidase family (GPXs) is an important member of antioxidant system which metabolizes intracellular ROS and maintains homeostasis of cells. Altered expressions of...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Chen, Baishen, Shen, Zhuojian, Wu, Duoguang, Xie, Xuan, Xu, Xia, Lv, Liangzhan, Dai, Honglue, Chen, Ju, Gan, Xiangfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457285/
https://ncbi.nlm.nih.gov/pubmed/31032363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7640547
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