Mouse skin passage of a Streptococcus pyogenes Tn917 mutant of sagA/pel restores virulence, beta-hemolysis and sagA/pel expression without altering the position or sequence of the transposon
BACKGROUND: Streptolysin S (SLS), the oxygen-stable hemolysin of Streptococcus pyogenes, has recently been shown to be encoded by the sagA/pel gene. Mutants lacking expression of this gene were less virulent in a dermonecrotic mouse infection model. Inactivation of the sagA/pel gene affect the expre...
Na minha lista:
| Publicado no: | BMC Microbiol |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2001
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11801184/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2180-1-33 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|