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A Probabilistic Model of the Germinal Center Reaction

Germinal centers (GCs) are specialized compartments within the secondary lymphoid organs, where B cells proliferate, differentiate, and mutate their antibody genes. Upon exit from the GC, B cells terminally differentiate into plasma cells or memory B cells. While we have a good comprehension of plas...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Thomas, Marcel Jan, Klein, Ulf, Lygeros, John, Rodríguez Martínez, María
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456718/
https://ncbi.nlm.nih.gov/pubmed/31001283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00689
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