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Direct measurement of the mechanical properties of a chromatin analog and the epigenetic effects of para-sulphonato-calix[4]arene

By means of Silicon Nano Tweezers (SNTs) the effects on the mechanical properties of λ-phage DNA during interaction with calf thymus nucleosome to form an artificial chromatin analog were measured. At a concentration of 100 nM, a nucleosome solution induced a strong stiffening effect on DNA (1.1 N m...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Tauran, Yannick, Kumemura, Momoko, Tarhan, Mehmet C., Perret, Grégoire, Perret, Florent, Jalabert, Laurent, Collard, Dominique, Fujita, Hiroyuki, Coleman, Anthony W.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456576/
https://ncbi.nlm.nih.gov/pubmed/30967623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42267-x
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