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Ropivacaine mesylate exerts neurotoxicity via up-regulation of Fas/FasL expression in rat pheochromocytoma PC12 cells

It has been shown that local anesthetics have potential neurotoxicity, but the exact mechanism remains unclear. In this study, PC12 cells were treated with different concentrations of ropivacaine mesylate (0.1, 0.5, 1, 2 and 4 mmol/L) for 24 h, the cell viability was assessed by CCK-8 assay. Then, c...

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Podrobná bibliografie
Vydáno v:Am J Transl Res
Hlavní autoři: Luo, Zhao, Zhang, Zhen, Zhang, Fuyu, Liu, Ying, Zhang, Yang, Sun, Xiaodong, Sang, Ming, Luo, Huiyu
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456514/
https://ncbi.nlm.nih.gov/pubmed/30972188
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