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Overarching Immunodominance Patterns and Substantial Diversity in Specificity and Functionality in the Circulating Human Influenza A and B Virus–Specific CD4(+) T-Cell Repertoire

There is limited information on the antigen specificity and functional potential of the influenza virus–specific CD4(+) T-cell repertoire in humans. Here, enzyme-linked immunospot assays were used to examine circulating CD4(+) T-cell specificities for influenza virus directly ex vivo in healthy adul...

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Podrobná bibliografie
Vydáno v:J Infect Dis
Hlavní autoři: Richards, Katherine A, Treanor, John J, Nayak, Jennifer L, Sant, Andrea J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455892/
https://ncbi.nlm.nih.gov/pubmed/29762692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy288
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