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41.1 EARLY LIFE STRESS COMBINED WITH PREFRONTAL DISRUPTION OF STRESS REGULATION RENDERS NORMAL RATS SUSCEPTIBLE TO THE EMERGENCE OF A HYPERDOPAMINERGIC STATE IN ADULTS
BACKGROUND: Our prior work on the MAM model of schizophrenia showed that MAM-treated offspring are anxious (as defined in the elevated plus maze), hyper-responsive to stressors (footshock evoked vocalization) and have a hyperactive amygdala prepubertally, before the dopaminergic changes arise. Furth...
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| Udgivet i: | Schizophr Bull |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6455518/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbz022.169 |
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