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32.2 TWO GLOBAL PHASE III TRIALS OF ENCENICLINE FOR COGNITIVE IMPAIRMENT IN CHRONIC SCHIZOPHRENIA PATIENTS: RED FLAGS AND LESSONS LEARNED
BACKGROUND: Multiple lines of evidence indicate that alterations of the α7 nicotinic acetylcholine receptor (nAChR) may play a role in the pathophysiology of several neuropsychiatric disorders that manifest with cognitive impairment, including schizophrenia. Encenicline (EVP-6124), a selective α7 nA...
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| Publicado no: | Schizophr Bull |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6455494/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbz022.133 |
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