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32.4 A NOVEL TREATMENT FOR COGNITIVE IMPAIRMENT ASSOCIATED WITH SCHIZOPHRENIA BY ENHANCING THE ACTIVITY OF PARVALBUMIN INTERNEURONS
BACKGROUND: Fast-spiking, parvalbumin-positive GABAergic interneurons in corticolimbic circuits modulate the synchronous firing of pyramidal neurons to enhance gamma-frequency oscillations which are thought to underpin cognitive function. Increasing evidence from post-mortem studies and animal model...
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| Publicado no: | Schizophr Bull |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6455279/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbz022.135 |
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