Hepatitis B virus mutation pattern rtL180M+A181C+M204V may contribute to entecavir resistance in clinical practice

Background and Aims: Entecavir (ETV) resistance of hepatitis B virus (HBV) conventionally requires rt184, 202, or 250 mutations plus lamivudine-resistance mutation (rtM204V/I ± L180M). This study aimed to clarify whether rtL180M+A181C+M204V mutations may contribute to HBV ETV resistance. Methods: Se...

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Detalhes bibliográficos
Publicado no:Emerg Microbes Infect
Main Authors: Liu, Yan, Zhou, Yi, Li, Xiaodong, Niu, Ming, Chen, Rongjuan, Shao, Jinman, Si, Lanlan, Luo, Dan, Lin, Yayun, Li, Le, Zhang, Kai, Xiao, Xiaohe, Xu, Zhihui, Liu, Min, Lu, Mengji, Zoulim, Fabien, Xu, Dongping
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455135/
https://ncbi.nlm.nih.gov/pubmed/30866789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2019.1584018
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