Inhibition of ATM reverses EMT and decreases metastatic potential of cisplatin-resistant lung cancer cells through JAK/STAT3/PD-L1 pathway

BACKGROUND: The cisplatin-resistance is still a main course for chemotherapy failure of lung cancer patients. Cisplatin-resistant cancer cells own higher malignance and exhibited increased metastatic ability, but the mechanism is not clear. In this study, we investigated the effects of Ataxia Telang...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Shen, Mingjing, Xu, Zhonghua, Xu, Weihua, Jiang, Kanqiu, Zhang, Fuquan, Ding, Qifeng, Xu, Zhonghen, Chen, Yongbing
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454747/
https://ncbi.nlm.nih.gov/pubmed/30961670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1161-8
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