Targeting the β2-integrin LFA-1, reduces adverse neuroimmune actions in neuropathic susceptibility caused by prenatal alcohol exposure

Recently, moderate prenatal alcohol exposure (PAE) was shown to be a risk factor for peripheral neuropathy following minor nerve injury. This effect coincides with elevated spinal cord astrocyte activation and ex vivo immune cell reactivity assessed by proinflammatory cytokine interleukin (IL) -1β p...

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Detalles Bibliográficos
Publicado en:Acta Neuropathol Commun
Autores principales: Sanchez, Joshua J., Sanchez, Jacob E., Noor, Shahani, Ruffaner-Hanson, Chaselyn D., Davies, Suzy, Wagner, Carston R., Jantzie, Lauren L., Mellios, Nikolaos, Savage, Daniel D., Milligan, Erin D.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454692/
https://ncbi.nlm.nih.gov/pubmed/30961664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0701-y
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