Fear-Potentiated Startle Response as an Endophenotype:Evaluating Metrics and Methods for Genetic Applications

The modulation of the startle response (SR) by threatening stimuli (fear-potentiated startle; FPS), is a proposed endophenotype for disorders of the fearful-fearlessness spectrum. FPS has failed to show evidence of heritability, raising concerns. However, the metrics used to index FPS – and, importa...

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Опубликовано в: :Psychophysiology
Главные авторы: Savage, Jeanne E., Moore, Ashlee A., Sawyers, Chelsea K., Bourdon, Jessica L., Verhulst, Brad, Carney, Dever M., Moroney, Elizabeth, Machlin, Laura, Kaabi, Oumaima, Vrana, Scott, Grillon, Christian, Brotman, Melissa A., Leibenluft, Ellen, Pine, Daniel S., Roberson-Nay, Roxann, Hettema, John M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454577/
https://ncbi.nlm.nih.gov/pubmed/30613993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/psyp.13325
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