DIMM-SC: a Dirichlet mixture model for clustering droplet-based single cell transcriptomic data

MOTIVATION: Single cell transcriptome sequencing (scRNA-Seq) has become a revolutionary tool to study cellular and molecular processes at single cell resolution. Among existing technologies, the recently developed droplet-based platform enables efficient parallel processing of thousands of single ce...

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Veröffentlicht in:Bioinformatics
Hauptverfasser: Sun, Zhe, Wang, Ting, Deng, Ke, Wang, Xiao-Feng, Lafyatis, Robert, Ding, Ying, Hu, Ming, Chen, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Special Issue: Recomb-Seq/Recomb-Ccb/Recomb-Cg
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454475/
https://ncbi.nlm.nih.gov/pubmed/29036318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx490
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