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‘Optimism bias’ in contemporary national clinical trial network phase III trials: are we improving?

BACKGROUND: Previous studies have found that overestimating treatment effects (i.e. ‘optimism bias’) leads to underpowered clinical trials. The prevalence of ‘optimism bias’ in contemporary National Clinical Trials Network (NCTN) cancer clinical trials is unknown. METHODS: We conducted a systematic...

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Detalhes bibliográficos
Publicado no:Ann Oncol
Main Authors: Zakeri, K, Noticewala, S S, Vitzthum, L K, Sojourner, E, Shen, H, Mell, L K
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454418/
https://ncbi.nlm.nih.gov/pubmed/30412223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdy340
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