Comparison of Mesenchymal Stromal Cells From Different Origins for the Treatment of Graft-vs.-Host-Disease in a Humanized Mouse Model

Mesenchymal stromal cells (MSCs) have potent immunomodulatory properties that make them an attractive tool against graft- vs.-host disease (GVHD). However, despite promising results in phase I/II studies, bone marrow (BM-) derived MSCs failed to demonstrate their superiority over placebo in the sole...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Grégoire, Céline, Ritacco, Caroline, Hannon, Muriel, Seidel, Laurence, Delens, Loïc, Belle, Ludovic, Dubois, Sophie, Vériter, Sophie, Lechanteur, Chantal, Briquet, Alexandra, Servais, Sophie, Ehx, Gregory, Beguin, Yves, Baron, Frédéric
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454068/
https://ncbi.nlm.nih.gov/pubmed/31001253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00619
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