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Estradiol-Mediated Axogenesis of Hypothalamic Neurons Requires ERK1/2 and Ryanodine Receptors-Dependent Intracellular Ca(2+) Rise in Male Rats
17β-estradiol (E2) induces axonal growth through extracellular signal-regulated kinase 1 and 2 (ERK1/2)-MAPK cascade in hypothalamic neurons of male rat embryos in vitro, but the mechanism that initiates these events is poorly understood. This study reports the intracellular Ca(2+) increase that par...
Bewaard in:
| Gepubliceerd in: | Front Cell Neurosci |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6454002/ https://ncbi.nlm.nih.gov/pubmed/31001087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00122 |
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