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Hepatic arginase 2 (Arg2) is sufficient to convey the therapeutic metabolic effects of fasting

Caloric restriction and intermittent fasting are emerging therapeutic strategies against obesity, insulin resistance and their complications. However, the effectors that drive this response are not completely defined. Here we identify arginase 2 (Arg2) as a fasting-induced hepatocyte factor that pro...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhang, Yiming, Higgins, Cassandra B., Fortune, Hannah M., Chen, Phillip, Stothard, Alicyn I., Mayer, Allyson L., Swarts, Benjamin M., DeBosch, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453920/
https://ncbi.nlm.nih.gov/pubmed/30962478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09642-8
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