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Development of a Protease Biosensor Based on a Dimerization-Dependent Red Fluorescent Protein
Dysregulated activity of the protease matriptase is a key contributor to aggressive tumor growth, cancer metastasis, and osteoarthritis. Methods for the detection and quantification of matriptase activity and inhibition would be useful tools. To address this need, we developed a matriptase-sensitive...
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| Udgivet i: | ACS Chem Biol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6453536/ https://ncbi.nlm.nih.gov/pubmed/29125730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00715 |
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