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Delivery of mRNA Therapeutics for the Treatment of Hepatic Diseases

Promising improvements in the field of transcript therapeutics have clearly enhanced the potential of mRNA as a new pillar for protein replacement therapies. Synthetic mRNAs are engineered to replace mutated mRNAs and to be immunologically inconspicuous and highly stable while maximizing protein exp...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Trepotec, Zeljka, Lichtenegger, Eva, Plank, Christian, Aneja, Manish K., Rudolph, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453508/
https://ncbi.nlm.nih.gov/pubmed/30655211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.12.012
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