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mRNA-Based Protein Replacement Therapy for the Heart

Myocardial infarction (MI) and heart failure (HF) are the leading causes of death in the United States and in most other industrialized nations. MI leads to a massive loss of cardiomyocytes (CMs), which are replaced with non-CM cells, leading to scarring and, in most cases, HF. The adult mammalian h...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Magadum, Ajit, Kaur, Keerat, Zangi, Lior
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453506/
https://ncbi.nlm.nih.gov/pubmed/30611663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.11.018
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