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Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection
Viral myocarditis is a serious disease, commonly caused by type B coxsackieviruses (CVB). Here we show that innate immune protection against CVB3 myocarditis requires the IFIT (IFN-induced with tetratricopeptide) locus, which acts in a biphasic manner. Using IFIT locus knockout (IFITKO) cardiomyocyt...
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| Publicat a: | PLoS Pathog |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6453442/ https://ncbi.nlm.nih.gov/pubmed/30958867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007674 |
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