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Targeting CD47 as a cancer therapeutic strategy – the cutaneous T cell lymphoma experience

PURPOSE OF REVIEW: To describe the relevance of CD47 in the tumor microenvironment and summarize data on anti-CD47 therapies, including its role in cutaneous T-cell lymphoma (CTCL). RECENT FINDINGS: CD47 is expressed on all normal cells and targets SIRPα on the surface of myeloid cells. However, CD4...

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Dades bibliogràfiques
Publicat a:Curr Opin Oncol
Autors principals: Folkes, Alecia S, Feng, Mingye, Zain, Jasmine M, Abdulla, Farah, Rosen, Steven T, Querfeld, Christiane
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452884/
https://ncbi.nlm.nih.gov/pubmed/29994903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000468
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