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Targeting CD47 as a cancer therapeutic strategy – the cutaneous T cell lymphoma experience
PURPOSE OF REVIEW: To describe the relevance of CD47 in the tumor microenvironment and summarize data on anti-CD47 therapies, including its role in cutaneous T-cell lymphoma (CTCL). RECENT FINDINGS: CD47 is expressed on all normal cells and targets SIRPα on the surface of myeloid cells. However, CD4...
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| Veröffentlicht in: | Curr Opin Oncol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6452884/ https://ncbi.nlm.nih.gov/pubmed/29994903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000468 |
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