Inhibition of osteocyte membrane repair activity via dietary Vitamin E deprivation impairs osteocyte survival

Osteocytes experience plasma membrane disruptions (PMD) that initiate mechanotransduction both in vitro and in vivo in response to mechanical loading, suggesting that osteocytes use PMD to sense and adapt to mechanical stimuli. PMD repair is crucial for cell survival; antioxidants (e.g., alpha-tocop...

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Detalhes bibliográficos
Publicado no:Calcif Tissue Int
Main Authors: Hagan, Mackenzie L., Bahraini, Anoosh, Pierce, Jessica L., Bass, Sarah M., Yu, Kanglun, Elsayed, Ranya, Elsalanty, Mohammed, Johnson, Maribeth H., McNeil, Anna, McNeil, Paul L., McGee-Lawrence, Meghan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452877/
https://ncbi.nlm.nih.gov/pubmed/30357446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-018-0487-0
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