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Pembrolizumab in the treatment of locally advanced or metastatic urothelial carcinoma: clinical trial evidence and experience

The treatment of advanced urothelial carcinoma (UC) has dramatically changed with the advent of immune checkpoint inhibitors that disrupt the T-cell inhibitory interaction between the programmed cell death (PD)-1 receptor and its ligand (PD-L1). Pembrolizumab, a highly specific, monoclonal antibody...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Ther Adv Urol
Hauptverfasser: Crist, Michael, Iyer, Gopa, Hsu, Miles, Huang, William C., Balar, Arjun V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452591/
https://ncbi.nlm.nih.gov/pubmed/31057668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756287219839285
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