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Pembrolizumab in the treatment of locally advanced or metastatic urothelial carcinoma: clinical trial evidence and experience

The treatment of advanced urothelial carcinoma (UC) has dramatically changed with the advent of immune checkpoint inhibitors that disrupt the T-cell inhibitory interaction between the programmed cell death (PD)-1 receptor and its ligand (PD-L1). Pembrolizumab, a highly specific, monoclonal antibody...

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Detalhes bibliográficos
Publicado no:Ther Adv Urol
Main Authors: Crist, Michael, Iyer, Gopa, Hsu, Miles, Huang, William C., Balar, Arjun V.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452591/
https://ncbi.nlm.nih.gov/pubmed/31057668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756287219839285
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