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Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues

Exposure to environmental chemicals has been shown to have an impact on the epigenome. One example is a known human carcinogen 1,3-butadiene which acts primarily by a genotoxic mechanism, but also disrupts the chromatin structure by altering patterns of cytosine DNA methylation and histone modificat...

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Detalles Bibliográficos
Publicado en:Arch Toxicol
Main Authors: Lewis, Lauren, Chappell, Grace A., Kobets, Tetyana, O’Brian, Bridget E., Sangaraju, Dewakar, Kosyk, Oksana, Bodnar, Wanda, Tretyakova, Natalia Y., Pogribny, Igor P., Rusyn, Ivan
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451682/
https://ncbi.nlm.nih.gov/pubmed/30552462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-018-2374-x
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