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Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues
Exposure to environmental chemicals has been shown to have an impact on the epigenome. One example is a known human carcinogen 1,3-butadiene which acts primarily by a genotoxic mechanism, but also disrupts the chromatin structure by altering patterns of cytosine DNA methylation and histone modificat...
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| Publicado no: | Arch Toxicol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6451682/ https://ncbi.nlm.nih.gov/pubmed/30552462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-018-2374-x |
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