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Genomic annotation of disease-associated variants reveals shared functional contexts

Variation in non-coding DNA, encompassing gene regulatory regions such as enhancers and promoters, contributes to risk for complex disorders, including type 2 diabetes. While genome-wide association studies have successfully identified hundreds of type 2 diabetes loci throughout the genome, the vast...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Kyono, Yasuhiro, Kitzman, Jacob O., Parker, Stephen C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451673/
https://ncbi.nlm.nih.gov/pubmed/30756131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-019-4823-3
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