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FXR Deficiency Alters Bile Acid Pool Composition and Exacerbates Chronic Alcohol Induced Liver Injury
Recent studies have investigated the roles of FXR deficiency in the pathogenesis of alcoholic liver disease (ALD). However, the underlined molecular mechanisms remain unclear. In this study, FXR knockout (FXR(−/−)) and wild-type (WT) mice were subjected to chronic-plus-binge alcohol feeding to study...
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| Publicado no: | Dig Liver Dis |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6451669/ https://ncbi.nlm.nih.gov/pubmed/30803859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dld.2018.12.026 |
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