Breast cancer cells rely on environmental pyruvate to shape the metastatic niche

Extracellular matrix (ECM) is a major component of the local environment, i.e. the niche, that can determine cell behavior1. During metastatic growth, cancer cells shape the ECM of the metastatic niche by hydroxylating collagen to promote their own metastatic growth2, 3. However, only particular nut...

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Bibliografske podrobnosti
izdano v:Nature
Main Authors: Elia, Ilaria, Rossi, Matteo, Stegen, Steve, Broekaert, Dorien, Doglioni, Ginevra, van Gorsel, Marit, Boon, Ruben, Escalona-Noguero, Carmen, Torrekens, Sophie, Verfaillie, Catherine, Verbeken, Erik, Carmeliet, Geert, Fendt, Sarah-Maria
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451642/
https://ncbi.nlm.nih.gov/pubmed/30814728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-0977-x
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