Constitutive STAT5 activation regulates Paneth and Paneth-like cells to control Clostridium difficile colitis

Clostridium difficile impairs Paneth cells, driving intestinal inflammation that exaggerates colitis. Besides secreting bactericidal products to restrain C. difficile, Paneth cells act as guardians that constitute a niche for intestinal epithelial stem cell (IESC) regeneration. However, how IESCs ar...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Life Sci Alliance
Prif Awduron: Liu, Ruixue, Moriggl, Richard, Zhang, Dongsheng, Li, Haifeng, Karns, Rebekah, Ruan, Hai-Bin, Niu, Haitao, Mayhew, Christopher, Watson, Carey, Bangar, Hansraj, Cha, Sang-wook, Haslam, David, Zhang, Tongli, Gilbert, Shila, Li, Na, Helmrath, Michael, Wells, James, Denson, Lee, Han, Xiaonan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Life Science Alliance LLC 2019
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451325/
https://ncbi.nlm.nih.gov/pubmed/30948494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900296
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