Activated STAT5 Confers Resistance to Intestinal Injury by Increasing Intestinal Stem Cell Proliferation and Regeneration

Intestinal epithelial stem cells (IESCs) control the intestinal homeostatic response to inflammation and regeneration. The underlying mechanisms are unclear. Cytokine-STAT5 signaling regulates intestinal epithelial homeostasis and responses to injury. We link STAT5 signaling to IESC replenishment up...

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Foilsithe in:Stem Cell Reports
Main Authors: Gilbert, Shila, Nivarthi, Harini, Mayhew, Christopher N., Lo, Yuan-Hung, Noah, Taeko K., Vallance, Jefferson, Rülicke, Thomas, Müller, Mathias, Jegga, Anil G., Tang, Wenjuan, Zhang, Dongsheng, Helmrath, Michael, Shroyer, Noah, Moriggl, Richard, Han, Xiaonan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2015
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325270/
https://ncbi.nlm.nih.gov/pubmed/25579133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.12.004
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