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Spatial regulation of the polarity kinase PAR-1 by parallel inhibitory mechanisms

The MARK/PAR-1 family of kinases are conserved regulators of cell polarity that share a conserved C-terminal kinase-associated domain (KA1). Localization of MARK/PAR-1 kinases to specific regions of the cell cortex is a hallmark of polarized cells. In Caenorhabditis elegans zygotes, PAR-1 localizes...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Folkmann, Andrew W., Seydoux, Geraldine
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451319/
https://ncbi.nlm.nih.gov/pubmed/30814118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.171116
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