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PCC0208027, a novel tyrosine kinase inhibitor, inhibits tumor growth of NSCLC by targeting EGFR and HER2 aberrations

PCC-0208027 is a novel tyrosine kinase inhibitor that has a strong inhibitory effect on epidermal growth factor receptor (EGFR)- or HER2-driven cancers. The aim is to assess the anti-tumor activity of PCC0208027 and related mechanisms in non-small cell lung cancer (NSCLC). We examined the activity o...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Dong, Qiuju, Yu, Pengfei, Ye, Liang, Zhang, Jianzhao, Wang, Hongbo, Zou, Fangxia, Tian, Jingwei, Kurihara, Hiroshi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451005/
https://ncbi.nlm.nih.gov/pubmed/30952931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42245-3
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