Autophagy regulates lipid metabolism through selective turnover of NCoR1

Selective autophagy ensures the removal of specific soluble proteins, protein aggregates, damaged mitochondria, and invasive bacteria from cells. Defective autophagy has been directly linked to metabolic disorders. However how selective autophagy regulates metabolism remains largely uncharacterized....

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Publicado no:Nat Commun
Main Authors: Saito, Tetsuya, Kuma, Akiko, Sugiura, Yuki, Ichimura, Yoshinobu, Obata, Miki, Kitamura, Hiroshi, Okuda, Shujiro, Lee, Hyeon-Cheol, Ikeda, Kazutaka, Kanegae, Yumi, Saito, Izumu, Auwerx, Johan, Motohashi, Hozumi, Suematsu, Makoto, Soga, Tomoyoshi, Yokomizo, Takehiko, Waguri, Satoshi, Mizushima, Noboru, Komatsu, Masaaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450892/
https://ncbi.nlm.nih.gov/pubmed/30952864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08829-3
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