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Cardiac xenografts show reduced survival in the absence of transgenic human thrombomodulin expression in donor pigs

A combination of genetic manipulations of donor organs and target specific immunosuppression are instrumental in achieving long-term cardiac xenograft survival. Recently, results from our preclinical pig-to-baboon heterotopic cardiac xenotransplantation model suggests that a three-pronged approach i...

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Détails bibliographiques
Publié dans:Xenotransplantation
Auteurs principaux: Singh, Avneesh K., Chan, Joshua L., DiChiacchio, Laura, Hardy, Naomi L., Corcoran, Philip C., Lewis, Billeta G.T., Thomas, Marvin. L., Burke, Allen P., Ayares, David, Horvath, Keith A., Mohiuddin, Muhammad M.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450784/
https://ncbi.nlm.nih.gov/pubmed/30290025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12465
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