Cardiac xenografts show reduced survival in the absence of transgenic human thrombomodulin expression in donor pigs

A combination of genetic manipulations of donor organs and target specific immunosuppression are instrumental in achieving long-term cardiac xenograft survival. Recently, results from our preclinical pig-to-baboon heterotopic cardiac xenotransplantation model suggests that a three-pronged approach i...

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Bibliographic Details
Published in:Xenotransplantation
Main Authors: Singh, Avneesh K., Chan, Joshua L., DiChiacchio, Laura, Hardy, Naomi L., Corcoran, Philip C., Lewis, Billeta G.T., Thomas, Marvin. L., Burke, Allen P., Ayares, David, Horvath, Keith A., Mohiuddin, Muhammad M.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450784/
https://ncbi.nlm.nih.gov/pubmed/30290025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12465
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