Antibody-mediated targeting of cleavage-specific OPN-T cell interactions

T cells are crucial players in obesity-mediated adipose tissue inflammation. We hypothesized that osteopontin (OPN), an inflammatory protein with enhanced activity when proteolytically cleaved, affects the number of viable T cells in adipose tissue and assessed inhibition of the interaction between...

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Vydáno v:PLoS One
Hlavní autoři: Wanko, Bettina, Tardelli, Matteo, Jürets, Alexander, Neuhofer, Angelika, Prager, Gerhard, Morser, John, Leung, Lawrence L., Staffler, Günther, Zeyda, Maximilian, Stulnig, Thomas M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450625/
https://ncbi.nlm.nih.gov/pubmed/30951532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214938
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