Peptide-based vaccination against OPN integrin binding sites does not improve cardio-metabolic disease in mice

Obesity causes insulin resistance via a chronic low-grade inflammation. This inflammation is characterized by elevated pro-inflammatory markers and macrophage accumulation in the adipose tissue (AT). AT inflammation is a key factor causing insulin resistance and thus type 2 diabetes, both linked to...

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Pubblicato in:Immunol Lett
Autori principali: Grün, Nicole G., Strohmeier, Karin, Moreno-Viedma, Veronica, Le Bras, Marie, Landlinger, Christine, Zeyda, Karina, Wanko, Bettina, Leitner, Lukas, Staffler, Günther, Zeyda, Maximilian, Stulnig, Thomas M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420116/
https://ncbi.nlm.nih.gov/pubmed/27639826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2016.09.006
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