A 3D CFD model of the interstitial fluid pressure and drug distribution in heterogeneous tumor nodules during intraperitoneal chemotherapy

Although intraperitoneal chemotherapy (IPC) has evolved into an established treatment modality for patients with peritoneal metastasis (PM), drug penetration into tumor nodules remains limited. Drug transport during IPC is a complex process that depends on a large number of different parameters (e.g...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Steuperaert, Margo, Debbaut, Charlotte, Carlier, Charlotte, De Wever, Olivier, Descamps, Benedicte, Vanhove, Christian, Ceelen, Wim, Segers, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450529/
https://ncbi.nlm.nih.gov/pubmed/30929523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1588423
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