Stearoyl CoA Desaturase Is Essential for Regulation of Endoplasmic Reticulum Homeostasis and Tumor Growth in Glioblastoma Cancer Stem Cells

Inherent plasticity and various survival cues allow glioblastoma stem-like cells (GSCs) to survive and proliferate under intrinsic and extrinsic stress conditions. Here, we report that GSCs depend on the adaptive activation of ER stress and subsequent activation of lipogenesis and particularly stear...

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Xehetasun bibliografikoak
Argitaratua izan da:Stem Cell Reports
Egile Nagusiak: Pinkham, Kelsey, Park, David Jaehyun, Hashemiaghdam, Arsalan, Kirov, Aleksandar B., Adam, Isam, Rosiak, Kamila, da Hora, Cintia C., Teng, Jian, Cheah, Pike See, Carvalho, Litia, Ganguli-Indra, Gitali, Kelly, Avalon, Indra, Arup K., Badr, Christian E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450460/
https://ncbi.nlm.nih.gov/pubmed/30930246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.02.012
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